图文详情
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.