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SIX4 antibody
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SIX4
原料试剂 研发实验室
价格
¥1140.00
品牌 菲恩生物/FineTest
地区 中国,湖北省,武汉市
货号 FNab07888
产地 国产
选择规格
100µg
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武汉菲恩生物科技有限公司
武汉菲恩生物科技有限公司
武汉
营业执照已审核
武汉菲恩生物科技有限公司(Wuhan Fine Biotech Co., Ltd.)面向国内外市场,专业研发、生产和销售ELISA试剂盒、抗体、蛋白及相关科研试剂。公司坐落于中国光谷生物城,建有现代化的研发中心和万级GMP生产车间,已整体通过欧盟CE认证、ISO 9001:2015质量管理体系认证,获得高新技术企业、瞪羚企业、3551人才、科技小巨人等多项荣誉;公司建有实验动物房、配备先进的实验仪器,以保证产品的品质和实验研究的准确可靠性。 公司由海内外教授、博士组成的研发和管理团队,拥有成熟的分子生物学技术、免疫学技术、蛋白表达纯化技术、抗体筛选及制备等生物学技术。现已研发生产ELISA试剂盒热门指标3000多种,包含10多种稀有种属试剂盒;鼠单抗,兔多抗一万余种经过验证的抗体,包含:标签抗体、内参抗体、流式抗体、磷酸化抗体等多个类别;多种标记/非标记二抗,针对兔、羊、小鼠、大鼠、人等多个种属,100多种标记二抗,标记物包括HRP、Biotin、FITC、Cy3、Alexa Fluor 488、Alexa Fluor 594等;提供蛋白产品7000多种,包括原核表达系统、真核表达系统、哺乳动物表达系统、昆虫表达系统,涵盖人类及常见种属的细胞因子,信号通路,诊断原料,受体蛋白,酶,抗原等。公司拥有一套严格的质控标准,生产出的产品均做过大量人和动物实验标本的检测。 公司产品在免疫学、信号转导、代谢、神经科学等领域内都有前沿科学文献发表,被国内外多所大学、研究机构和药学平台使用并发表文献达4000多次。公司凭借优异的产品和完善的服务体系受到国内外广大用户的青睐和认可;公司愿成为您的科研好帮手,专业生产商。
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产品规格 图文详情 技术文档
产品规格
品牌名称
菲恩生物/FineTest
货号
FNab07888
国产/进口
国产
规格
100µg
储存条件
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
发货地
武汉
供货方式
现货
使用范围
ELISA, WB
测量范围
WB: 1:500-1:2000
货源
新品
图文详情
Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a DNA sequence on these target genes and is involved in processes like cell differentiation, cell migration and cell survival. Transactivates gene expression by binding a 5'-[CAT]A[CT][CT][CTG]GA[GAT]-3' motif present in the Trex site and a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 site of the muscle-specific genes enhancer. Acts cooperatively with EYA proteins to transactivate their target genes through interaction and nuclear translocation of EYA protein. Acts synergistically with SIX1 to regulate target genes involved in formation of various organs, including muscle, kidney, gonad, ganglia, olfactory epithelium and cranial skeleton. Plays a role in several important steps of muscle development. Controls the genesis of hypaxial myogenic progenitors in the dermomyotome by transactivating PAX3 and the delamination and migration of the hypaxial precursors from the ventral lip to the limb buds through the transactivation of PAX3, MET and LBX1. Controls myoblast determination by transactivating MYF5, MYOD1 and MYF6. Controls somitic differentiation in myocyte through MYOG transactivation. Plays a role in synaptogenesis and sarcomere organization by participating in myofiber specialization during embryogenesis by activating fast muscle program in the primary myotome resulting in an up-regulation of fast muscle genes, including ATP2A1, MYL1 and TNNT3. Simultaneously, is also able to activate inhibitors of slow muscle genes, such as SOX6, HRASLS, and HDAC4, thereby restricting the activation of the slow muscle genes. During muscle regeneration, negatively regulates differentiation of muscle satellite cells through down-regulation of MYOG expression. During kidney development regulates the early stages of metanephros development and ureteric bud formation through regulation of GDNF, SALL1, PAX8 and PAX2 expression. Plays a role in gonad development by regulating both testis determination and size determination. In gonadal sex determination, transactivates ZFPM2 by binding a MEF3 consensus sequence, resulting in SRY up-regulation. In gonadal size determination, transactivates NR5A1 by binding a MEF3 consensus sequence resulting in gonadal precursor cell formation regulation. During olfactory development mediates the specification and patterning of olfactory placode through fibroblast growth factor and BMP4 signaling pathways and also regulates epithelial cell proliferation during placode formation. Promotes survival of sensory neurons during early trigeminal gangliogenesis. In the developing dorsal root ganglia, up-regulates SLC12A2 transcription. Regulates early thymus/parathyroid organogenesis through regulation of GCM2 and FOXN1 expression. Forms gustatory papillae during development of the tongue. Also plays a role during embryonic cranial skeleton morphogenesis.
技术文档
文件菲恩公司介绍单页.pdf
2.24MB 查看资料
文件特别推荐易拉宝.pdf
1.55MB 查看资料
文件菲恩生物抗体画册.pdf
5.2MB 查看资料
文件抗体二折页.pdf
3.85MB 查看资料
文件抗体易拉宝.pdf
1.34MB 查看资料
文件流式抗体产品资料.pdf
2.59MB 查看资料
文件流式配色服务单页.pdf
1.79MB 查看资料
文件特别推荐产品.pdf
1.88MB 查看资料
文件抗体CMC产品_CN (带水印).pdf
2.3MB 查看资料
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