图文详情
WBS15, also named as LAB, NTAL, WBSCR15, WBSCR5and LAT2(Linker for activation of T-cells family member 2; not SLC7A8/LAT2), is involved in FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast and myeloid cells. WBS15 is involved in BCR(B-cell antigen receptor)-mediated signaling in B-cells. It is located in the Williams-Beuren syndrome(WBS) critical region. WBS15 has two isoform with MW 27-30 kDa and 12 kDa.