图文详情
mRNA-binding protein involved in post-transcriptional regulation of AU-rich element(ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7(and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor(TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor(TNF).