Jotbodyanti-CD3 VHH antibody, clone CH99JOT0146Jotbody ,捷博-易享

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anti-CD3 VHH antibody, clone CH99

Alpaca derived anti-CD3 VHH single domain antibody clone CH99 (molecular weight: 17.1 kDa), expressed in E. coli under conditions free from animal derived components

原料试剂研发实验室

价格

￥960.00-9435.00

品牌 Jotbody

地区中国,香港特别行政区,新界

货号 JOT0146

产地进口

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50 ug

100 ug

1000 ug

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Jotbody 捷博生物

深圳市捷博生物科技有限公司

深圳

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Jotbody（捷博生物）成立于2020年，专注纳米抗体和外泌体领域，提供专业CRO服务及优质试剂产品。公司系香港城市大学孵化，由生物制药与生命科学工具领域的顶尖大学教授、资深企业家和海归博士共同创立，搭建先进纳米抗体发现平台、工程化外泌体平台和高性能试剂开发平台，研发创新试剂适配科研、分析检测及诊断多场景。作为国家高新技术企业，《福布斯亚洲》“2023年亚洲最值得关注100家企业”，服务已覆盖30余个国家和地区。

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产品规格图文详情技术文档

产品规格

品牌名称

Jotbody

货号

JOT0146

国产/进口

进口

规格

50 ug,100 ug,1000 ug

货源

新品

图文详情

Basic Information

Specificity	Species Reactivity	Clone	Conjugate and Tags	Tested Applications
CD3 epsilon, CD3e, T-Cell Surface Glycoprotein CD3 Epsilon Chain	Human	CH99	Un-conjugated; with HA and LPETG tags at its C-terminal	IF
Purification	Product Buffer Solution	Format	Reconstitution	Analyte Description
Affinity chromatography purified via Ni-charged resin	PBS, pH 7.4	Lyophilized	Reconstitute the lyophilized protein with sterile deionized water or with 50% glycerol (ACS grade or better) to a stock solution of 1 mg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.	The CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. The genes encoding the CD3 epsilon, gamma and delta polypeptides are located on chromosome 11. Defects in the CD3 gene are associated with CD3 immunodeficiency.

Parameters on Each Lot

Product Concentration	Purity	Recommended Dilutions
1 mg/mL by Nanodrop	≥95% (4-12% gradient SDS-PAGE)	IF 1:200-1:800

技术文档

Datasheet for JOT0146.pdf

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