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anti-α-synuclein VHH antibody, clone L46
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Alpaca derived Anti-α-synuclein single domain antibody clone L46 (molecular weight: 16.47 kDa), expressed in E. coli under conditions free from animal derived components
原料试剂 研发实验室
价格
¥960.00-9435.00
品牌 Jotbody
地区 中国,香港特别行政区,新界
货号 JOT0134
产地 进口
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50 ug
100 ug
1000 ug
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Jotbody 捷博生物
深圳市捷博生物科技有限公司
深圳
营业执照已审核
Jotbody(捷博生物)成立于2020年,专注纳米抗体和外泌体领域,提供专业CRO服务及优质试剂产品。公司系香港城市大学孵化,由生物制药与生命科学工具领域的顶尖大学教授、资深企业家和海归博士共同创立,搭建先进纳米抗体发现平台、工程化外泌体平台和高性能试剂开发平台,研发创新试剂适配科研、分析检测及诊断多场景。作为国家高新技术企业,《福布斯亚洲》“2023年亚洲最值得关注100家企业”,服务已覆盖30余个国家和地区。
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产品规格 图文详情 技术文档
产品规格
品牌名称
Jotbody
货号
JOT0134
国产/进口
进口
规格
50 ug,100 ug,1000 ug
货源
新品
图文详情

Basic Information

SpecificitySpecies ReactivityCloneConjugate and TagsTested Applications
Synuclein Alpha , SNCA, α-synucleinHumanL46Un-conjugated; with HA, LPETG and8*His tags at its C-terminalIHC
PurificationProduct Buffer SolutionFormatAnalyte Description 
Affinity chromatography purified via Ni-charged resin25 mM TAPS pH8.5, 500 mM NaCl, 5 mM EDTA, 0.1 % Proclin 300 SolutionLiquidAlpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways. Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease. Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body. 

 

Parameters on Each Lot

Product ConcentrationPurityRecommended
Dilutions
  
0.626 mg/mL by Nanodrop≥95% (4-12% gradient SDS-PAGE)IHC 1:50-1:250  
技术文档
文件Datasheet for JOT0134.pdf
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