产品概述
| 产品名称(Product Name) | Apg12 (18O8) Rabbit Monoclonal Antibody |
| 描述(Description) | Rabbit Monoclonal Antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB |
| 种属反应性(Reactivity) | Human |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Monoclonal |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA. |
| 纯化方式(Purification) | Affinity purification |
免疫原
| 免疫原信息(Immunogen Information) | 0 |
| 基因名(Gene Name) | ATG12 |
| 别名(Alternative Names) | APG12-like; APG12L; ATG12; Autophagy 12; FBR93; HAPG12; |
| 基因ID(Gene ID) | 9140 |
| 蛋白ID(SwissProt ID) | O94817 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1:1000-1:5000 |
| 蛋白分子量(Molecular Weight) | 15kDa |
研究背景
Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
研究领域