产品概述
| 产品名称(Product Name) | REA (13I14) Rabbit Monoclonal Antibody |
| 描述(Description) | Rabbit Monoclonal Antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB |
| 种属反应性(Reactivity) | Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Monoclonal |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA. |
| 纯化方式(Purification) | Affinity purification |
免疫原
| 免疫原信息(Immunogen Information) | 0 |
| 基因名(Gene Name) | PHB2 {ECO:0000312|EMBL:AAH14766.1, ECO:0000312|HGNC:HGNC:30306} |
| 别名(Alternative Names) | BAP; Bap37; BCAP 37; D prohibitin; p22; Phb2; PNAS 141; Prohibitin 2; |
| 基因ID(Gene ID) | 11331 |
| 蛋白ID(SwissProt ID) | Q99623 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1:2000-1:10000 |
| 蛋白分子量(Molecular Weight) | 33kDa |
研究背景
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Protein with pleiotropic attributes mediated in a cell- compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors and sex steroid hormones in the nucleus.
研究领域