产品概述
| 产品名称(Product Name) | GADD 45γ Rabbit Polyclonal Antibody |
| 描述(Description) | Rabbit Polyclonal Antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,IF,IHC, |
| 种属反应性(Reactivity) | Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Polyclonal |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| 纯化方式(Purification) | Affinity purification |
免疫原
| 基因名(Gene Name) | GADD45G |
| 别名(Alternative Names) | GADD45G; CR6; DDIT2; Growth arrest and DNA damage-inducible protein GADD45 gamma; Cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; DDIT-2 |
| 基因ID(Gene ID) | 10912 |
| 蛋白ID(SwissProt ID) | O95257 |
产品应用
| 稀释比(Dilution Ratio) | WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. |
| 蛋白分子量(Molecular Weight) | 19kD |
研究背景
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008],function:Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.,similarity:Belongs to the GADD45 family.,subunit:Interacts with GADD45GIP1.,
研究领域
MAPK_ERK_Growth;MAPK_G_Protein;Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;p53;