产品概述
| 产品名称(Product Name) | CD42b (1R11) Rabbit Monoclonal Antibody |
| 描述(Description) | Rabbit Monoclonal Antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,ELISA |
| 种属反应性(Reactivity) | Human |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Monoclonal |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| 纯化方式(Purification) | Affinity purification |
免疫原
| 免疫原信息(Immunogen Information) | 0 |
| 基因名(Gene Name) | GP1BA |
| 别名(Alternative Names) | Antigen CD42b alpha; BDPLT1; BDPLT3; BSS; CD42b alpha; DBPLT3; Glycoprotein Ibalpha; GP Ib alpha; GP1B; GP1BA; GPIb alpha; GPIbA; VWDP; |
| 基因ID(Gene ID) | 2811 |
| 蛋白ID(SwissProt ID) | P07359 |
产品应用
| 稀释比(Dilution Ratio) | WB 1:1000-1:5000 |
| 蛋白分子量(Molecular Weight) | 72kDa |
研究背景
CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF. GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
研究领域