产品概述
| 产品名称（Product Name） | CD68 (6P4) Rabbit Monoclonal Antibody |
| 描述（Description） | Rabbit Monoclonal Antibody |
| 宿主（Host） | Rabbit |
| 应用（Application） | WB,ELISA |
| 种属反应性（Reactivity） | Human,Mouse,Rat |
产品性能
| 偶联物（Conjugation） | Unconjugated |
| 修饰（Modification） | Unmodified |
| 同种型（Isotype） | IgG |
| 克隆（Clonality） | Monoclonal |
| 形式（Form） | Liquid |
| 存放说明（Storage） | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液（Buffer） | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| 纯化方式（Purification） | Affinity purification |
免疫原
| 免疫原信息（Immunogen Information） | 0 |
| 基因名（Gene Name） | CD68 |
| 别名（Alternative Names） | CD68 antigen; CD68 molecule; Gp110; LAMP4; Macrophage antigen CD68 (microsialin); Macrosialin; SCARD1; Scavenger receptor class D member 1; |
| 基因ID（Gene ID） | 968 |
| 蛋白ID（SwissProt ID） | P34810 |
产品应用
| 稀释比（Dilution Ratio） | WB 1:500~1:1000 |
| 蛋白分子量（Molecular Weight） | 37kDa |
研究背景
CD68 belongs to a family of acidic, highly glycosylated lysosomal glycoproteins (LGPs) that includes lamp-1 and lamp-2. Play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
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