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This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],function:Orphan receptor. Seems to act through a G(q/11)-mediated pathway.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues.,

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