产品概述
| 产品名称(Product Name) | Orexin R-1 Rabbit Polyclonal Antibody |
| 描述(Description) | Rabbit Polyclonal Antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,ELISA |
| 种属反应性(Reactivity) | Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Polyclonal |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| 纯化方式(Purification) | Affinity purification |
免疫原
| 免疫原信息(Immunogen Information) | 0 |
| 基因名(Gene Name) | HCRTR1 |
| 别名(Alternative Names) | HCRTR1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1 |
| 基因ID(Gene ID) | 3061 |
| 蛋白ID(SwissProt ID) | O43613 |
产品应用
| 稀释比(Dilution Ratio) | WB 1:500 - 1:2000. ELISA: 1:5000. |
| 蛋白分子量(Molecular Weight) | 50kD |
研究背景
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009],function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.,similarity:Belongs to the G-protein coupled receptor 1 family.,
研究领域
Neuroactive ligand-receptor interaction;