产品概述
| 产品名称(Product Name) | Oncogene TIM Rabbit Polyclonal Antibody |
| 描述(Description) | Rabbit Polyclonal Antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,ELISA |
| 种属反应性(Reactivity) | Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Polyclonal |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| 纯化方式(Purification) | Affinity purification |
免疫原
| 免疫原信息(Immunogen Information) | 0 |
| 基因名(Gene Name) | ARHGEF5 |
| 别名(Alternative Names) | ARHGEF5; TIM; Rho guanine nucleotide exchange factor 5; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM |
| 基因ID(Gene ID) | 7984 |
| 蛋白ID(SwissProt ID) | Q12774 |
产品应用
| 稀释比(Dilution Ratio) | WB 1:500 - 1:2000. ELISA: 1:20000 |
| 蛋白分子量(Molecular Weight) | 60kD |
研究背景
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008],similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Mainly expressed in kidney, liver, pancreas, lung and placenta.,
研究领域
Regulation of Actin Dynamics; AMPK