产品概述
| 产品名称(Product Name) | Bcl-2 (phospho Ser70) Rabbit Polyclonal Antibody |
| 描述(Description) | Rabbit Polyclonal Antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,ELISA |
| 种属反应性(Reactivity) | Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Phospho Antibody |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Polyclonal |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| 纯化方式(Purification) | Affinity purification |
免疫原
| 免疫原信息(Immunogen Information) | 0 |
| 基因名(Gene Name) | BCL2 |
| 别名(Alternative Names) | BCL2; Apoptosis regulator Bcl-2 |
| 基因ID(Gene ID) | 24224 |
| 蛋白ID(SwissProt ID) | P49950 |
产品应用
| 稀释比(Dilution Ratio) | WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications. |
| 蛋白分子量(Molecular Weight) | 26kD |
研究背景
BCL2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
研究领域
Stem cell pathway; PI3K/Akt; NF_kappaB