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The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],catalytic activity:1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.,function:Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Testis-specific.,

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