产品概述
| 产品名称(Product Name) | Ubiquitin Protein Ligase E3A Rabbit Monoclonal Antibody |
| 描述(Description) | Recombinant Rabbit Monoclonal antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,ICC/IF |
| 种属反应性(Reactivity) | Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | UBE3A |
| 别名(Alternative Names) | Ubiquitin-protein ligase E3A; UBE3A; E6AP; EPVE6AP; HPVE6A |
| 基因ID(Gene ID) | 7337 |
| 蛋白ID(SwissProt ID) | Q05086 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 101 kDa; Observed MW: 101 kDa |
研究背景
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B.
研究领域
Epigenetics and Nuclear Signaling