产品概述
| 产品名称(Product Name) | PAK2 (7H3) Mouse Monoclonal Antibody |
| 描述(Description) | Primary antibody |
| 宿主(Host) | Mouse |
| 应用(Application) | WB,IHC,ICC/IF |
| 种属反应性(Reactivity) | Human,Monkey |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG1 |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式(Purification) | Ascitic Fluid |
免疫原
| 基因名(Gene Name) | PAK2 |
| 别名(Alternative Names) | PAK2; Serine/threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58 |
| 基因ID(Gene ID) | 5062 |
| 蛋白ID(SwissProt ID) | Q13177 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 58 kDa; Observed MW: 61 kDa |
研究背景
The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD.
研究领域
Cell Biology