产品概述
| 产品名称(Product Name) | Superoxide Dismutase 1 Rabbit Polyclonal Antibody |
| 描述(Description) | Primary antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB |
| 种属反应性(Reactivity) | Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Polyclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | SOD1 |
| 别名(Alternative Names) | SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1 |
| 基因ID(Gene ID) | 6647 |
| 蛋白ID(SwissProt ID) | P00441 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 16 kDa; Observed MW: 16 kDa |
研究背景
SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.
研究领域
Signal Transduction