产品概述
| 产品名称(Product Name) | LIN28A (9G2) Mouse Monoclonal Antibody |
| 描述(Description) | Primary antibody |
| 宿主(Host) | Mouse |
| 应用(Application) | WB,ICC/IF |
| 种属反应性(Reactivity) | Human |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG1 |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式(Purification) | Ascitic Fluid |
免疫原
| 基因名(Gene Name) | LIN28A |
| 别名(Alternative Names) | CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; Zinc finger CCHC domain-containing protein 1. |
| 基因ID(Gene ID) | 79727 |
| 蛋白ID(SwissProt ID) | Q9H9Z2 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 IF: 1/50-1/200 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 23 kDa; Observed MW: 23 kDa |
研究背景
Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.
研究领域
Epigenetics and Nuclear Signaling