产品概述
| 产品名称(Product Name) | CYP11B2 Rabbit Monoclonal Antibody |
| 描述(Description) | Recombinant Rabbit Monoclonal antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB |
| 种属反应性(Reactivity) | Human |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | CYP11B2 |
| 别名(Alternative Names) | CPN2; ALDOS; CYP11B; CYP11BL; CYPXIB2; P450C18; P-450C18; P450aldo |
| 基因ID(Gene ID) | 1585 |
| 蛋白ID(SwissProt ID) | P19099 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 |
| 蛋白分子量(Molecular Weight) | Calculated MW:58 kDa;Observed MW: 45 kDa |
研究背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
研究领域
Cardiovascular