产品概述
| 产品名称(Product Name) | HDAC4 (4A3) Mouse Monoclonal Antibody |
| 描述(Description) | Primary antibody |
| 宿主(Host) | Mouse |
| 应用(Application) | WB,IP |
| 种属反应性(Reactivity) | Human,Mouse,Rat,Monkey |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG2a |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | HDAC4 |
| 别名(Alternative Names) | EC 3.5.1.98; HA6116; HD 4; HD4; HDAC 4; HDAC A; HDAC4; HDAC4_HUMAN; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288. |
| 基因ID(Gene ID) | 9759 |
| 蛋白ID(SwissProt ID) | P56524 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 IP: 1/20 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 119 kDa; Observed MW: 140 kDa |
研究背景
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
研究领域
Epigenetics and Nuclear Signaling