产品概述
| 产品名称(Product Name) | Acetyl-p53 (Lys382) (3E3) Mouse Monoclonal Antibody |
| 描述(Description) | Primary antibody |
| 宿主(Host) | Mouse |
| 应用(Application) | IHC |
| 种属反应性(Reactivity) | Human,Rat,Mouse |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Acetylated |
| 同种型(Isotype) | IgG1 |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | TP53 |
| 别名(Alternative Names) | Cellular tumor antigen p53; Cys 51 stop; Tp53; Tumor protein p53 |
| 基因ID(Gene ID) | 7157 |
| 蛋白ID(SwissProt ID) | P04637 |
产品应用
| 稀释比(Dilution Ratio) | IHC: 1/50-1/100 |
| 蛋白分子量(Molecular Weight) | - |
研究背景
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
研究领域
Cell Biology