产品概述
| 产品名称(Product Name) | CD130 Rabbit Polyclonal Antibody |
| 描述(Description) | Primary antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,IHC |
| 种属反应性(Reactivity) | Human,Mouse |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Polyclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | IL6ST |
| 别名(Alternative Names) | Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130 |
| 基因ID(Gene ID) | 3572 |
| 蛋白ID(SwissProt ID) | P40189 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 IHC: 1/50-1/100 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 104 kDa; Observed MW: 130-140kDa |
研究背景
The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.
研究领域
Cell Biology