产品概述
| 产品名称(Product Name) | BRG1 (4E11) Mouse Monoclonal Antibody |
| 描述(Description) | Primary antibody |
| 宿主(Host) | Mouse |
| 应用(Application) | WB,IP |
| 种属反应性(Reactivity) | Human |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Unmodified |
| 同种型(Isotype) | IgG1 |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | SMARCA4 |
| 别名(Alternative Names) | SMARCA4; BAF190A; BRG1; SNF2B; SNF2L4; Transcription activator BRG1; ATP-dependent helicase SMARCA4; BRG1-associated factor 190A; BAF190A; Mitotic growth and transcription activator; Protein BRG-1; Protein brahma homolog 1; SNF2-beta; SWI/S |
| 基因ID(Gene ID) | 6597 |
| 蛋白ID(SwissProt ID) | P51532 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 IP: 1/20 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 185 kDa; Observed MW: 220 kDa |
研究背景
ATP-dependent chromatin remodeling complexes play an essential role in the regulation of various nuclear processes, such as gene expression, DNA replication, and repair. Acts as a corepressor of ZEB1 to regulate E-cadherin transcription and is required for induction of epithelial-mesenchymal transition (EMT) by ZEB1.
研究领域
Neuroscience