已关闭
收藏| 产品名称 |
Recombinant Human BPGM (C-6His) |
| 英文名称 |
Bisphosphoglycerate mutase/BPGM |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Bisphosphoglycerate Mutase is produced by our E.coli expression system and the target gene encoding Ser2-Lys259 is expressed with a 6His tag at the C-terminus. |
| Accession |
P07738 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
31 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, pH 8.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Bisphosphoglycerate Mutase; BPGM; 2;3-Bisphosphoglycerate Mutase Erythrocyte; 2;3-Bisphosphoglycerate Synthase; 2;3-Diphosphoglycerate Mutase; DPGM; BPG-Dependent PGAM; BPGM |
| 背景介绍 |
| Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia. |
注意事项
本司产品仅用于科研,不用于临床诊断和治疗