| 产品名称 | GMP Recombinant Human Tissue Factor |
| 蛋白名 | Tissue Factor |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 | ≤10 EU/mg |
| 蛋白构建 | Recombinant Human Tissue Factor is produced by our Mammalian cell expression system and the target gene encoding Ser33-Glu251 is expressed. |
| Accession # | P13726 |
| 蛋白标签 | Tag free |
| 表达宿主 | Mammalian cell |
| 种属 | Human |
| 预测分子量 | 23.98 kDa |
| 蛋白形态 | Lyophilized |
| 储存缓冲液 | PBS,5% mannitol and 0.01% Tween 80, pH7.4 |
| 运输方式 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
分子别名
Tissue Factor; TF; Coagulation Factor III; Thromboplastin; CD142; F3
蛋白活性

背景介绍
Full-length tissue factor (TF) is a transmembrane receptor and cofactor for factor (F)VII/FVIIa. In addition to full-length TF, an alternative spliced (as) form of TF can be generated that lacks the transmembrane domain and is released fromcells. In contrast to TF, asTF has low procoagulant activity because it lacks the transmembrane domain. Tissue factor is expressed by cells around blood vessels, such as adventitial fibroblasts, and body surfaces, such as epithelial cells, and plays a critical role in hemostasis. TF also contributes to various forms of thrombosis. Many cancers, particularly adenocarcinomas, express high levels of TF. A high level of tumor TF expression is associated with poor prognosis in many types of cancers, including breast, prostate, colorectal, and pancreatic cancer.