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Recombinant Mouse Tpsb2 (C-6His)
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原料试剂 研发实验室
价格
¥6000.00
品牌 EnkiLife/恩玑
地区 中国,湖北省,武汉市
货号 PHM1929
产地 国产
选择规格
50µg
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EnkiLife
武汉EnkiLife-log科技有限公司
武汉
营业执照已审核
武汉恩玑生命科技有限公司(EnkiLife)是一家聚焦细胞生物学和免疫学的生物技术企业,致力于为生命科学行业的科研工作者提供高质量的产品和卓越的客户服务。 EnkiLife的产品线包括细胞系、原代细胞、培养基、血清、细胞检测试剂盒、蛋白、抗体、ELISA试剂盒、生化试剂盒等,并提供技术服务与定制开发,全方位满足生命科学行业需求,为您的实验保驾护航! EnkiLife的技术团队凭借在生物科学领域的丰富经验和专业知识,已在公司内部构建了一套完善的技术平台,涵盖细胞培养及检测、蛋白表达、抗体制备以及免疫学等多个关键领域。我们始终秉承严格的质量管理体系,优化生产流程,确保为客户提供高效、精准的技术支持。 展望未来,EnkiLife将继续致力于技术创新,不断丰富和完善我们的技术平台,以更好地满足客户需求,同时不断提升服务水平,确保客户体验的持续优化。我们期待与更多的全球科研工作者携手合作,共同推动生命科学领域的进步与发展。
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产品规格 图文详情 技术文档
产品规格
品牌名称
EnkiLife/恩玑
货号
PHM1929
国产/进口
国产
规格
50µg
图文详情
产品名称

Recombinant Mouse Tpsb2 (C-6His)

英文名称

Mcpt6/Mast Cell Protease-6/mMCP-6/Tpsb2/Tryptase beta-2  

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素

<1 EU/µg as determined by LAL test.

蛋白构建

Recombinant Mouse Tryptase Beta-2 is produced by our Mammalian expression system and the target gene encoding Ala22-Ser276 is expressed with a 6His tag at the C-terminus.

Accession

P21845

表达宿主

Human Cells

种属

Mouse

预测分子量

29.3 KDa

制剂

Supplied as a 0.2 μm filtered solution of PBS, 1mM EDTA, pH 8.0.

运输方式

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

稳定性&储存

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

复溶

 

分子别名
Tryptase beta-2; Tryptase-2; Mast cell protease 6; mMCP-6

 

背景介绍
Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It plays a role in innate immunity. Tpsb2 can be detected primarily in skin during embryogenesis. Tpsb2 can not be detected at early embryonic stages but is abundantly expressed in later stages with a peak at E17.5-E18.5. Tryptase is a homotetramer. The active tetramer is converted to inactive monomers at neutral and acidic pH in the absence of heparin. Low concentrations of inactive monomers become active monomers at pH 6.0 in the presence of heparin. When the concentration of active monomers is higher, they convert to active monomers and then to active tetramers. These monomers are active and functionally distinct from the tetrameric enzyme. In contrast to the hidden active sites in the tetrameric form, the active site of the monomeric form is accessible for macromolecular proteins and inhibitors eg: fibrinogen which is a substrate for the monomeric but not for the tetrameric form. The monomeric form forms a complex with SERPINB6.

 

注意事项

本司产品仅用于科研,不用于临床诊断和治疗

 

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