| 产品名称 | GMP Recombinant Human FGF-7/KGF |
| 蛋白名 | FGF-7/KGF |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 | ≤10 EU/mg |
| 蛋白构建 | Recombinant Human FGF-7/KGF is produced by our Mammalian cell expression system and the target gene encoding Cys32-Thr194 is expressed. |
| Accession # | P21781 |
| 蛋白标签 | Tag free |
| 表达宿主 | Mammalian cell |
| 种属 | Human |
| 预测分子量 | 18.8 kDa |
| 蛋白形态 | Lyophilized |
| 储存缓冲液 | PBS,5% mannitol and 0.01% Tween 80, pH7.4 |
| 运输方式 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
分子别名
Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF
蛋白活性
The ED50 for this effect is ≤10 ng/mL.
背景介绍
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
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