EnkiLife/恩玑Recombinant Human IDO2 (C-6His)PEH1892EnkiLife,恩玑-易享

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Recombinant Human IDO2 (C-6His)

原料试剂研发实验室

价格

￥3180.00

品牌 EnkiLife/恩玑

地区中国,湖北省,武汉市

货号 PEH1892

产地国产

选择规格

50µg

易享客服

EnkiLife

武汉EnkiLife-log科技有限公司

武汉

营业执照已审核

武汉恩玑生命科技有限公司（EnkiLife）是一家聚焦细胞生物学和免疫学的生物技术企业，致力于为生命科学行业的科研工作者提供高质量的产品和卓越的客户服务。 EnkiLife的产品线包括细胞系、原代细胞、培养基、血清、细胞检测试剂盒、蛋白、抗体、ELISA试剂盒、生化试剂盒等，并提供技术服务与定制开发，全方位满足生命科学行业需求，为您的实验保驾护航！ EnkiLife的技术团队凭借在生物科学领域的丰富经验和专业知识，已在公司内部构建了一套完善的技术平台，涵盖细胞培养及检测、蛋白表达、抗体制备以及免疫学等多个关键领域。我们始终秉承严格的质量管理体系，优化生产流程，确保为客户提供高效、精准的技术支持。展望未来，EnkiLife将继续致力于技术创新，不断丰富和完善我们的技术平台，以更好地满足客户需求，同时不断提升服务水平，确保客户体验的持续优化。我们期待与更多的全球科研工作者携手合作，共同推动生命科学领域的进步与发展。

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产品规格图文详情技术文档

产品规格

品牌名称

EnkiLife/恩玑

货号

PEH1892

国产/进口

国产

规格

50µg

图文详情

产品名称	Recombinant Human IDO2 (C-6His)
英文名称	IDO-2/INDOL1
纯度	Greater than 95% as determined by reducing SDS-PAGE
内毒素	<1 EU/µg as determined by LAL test.
蛋白构建	Recombinant Human Indoleamine 2,3-dioxygenase 2 is produced by our E.coli expression system and the target gene encoding Met14-Gly420 is expressed with a 6His tag at the C-terminus.
Accession	Q6ZQW0
表达宿主	E.coli
种属	Human
预测分子量	46.5 KDa
制剂	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, 1mM EDTA, 250mM NaCl, pH 8.0.
运输方式	The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.
稳定性&储存	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
复溶

分子别名

Indoleamine 2,3-dioxygenase 2; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1; IDO2; INDOL1

背景介绍

Indoleamine 2,3-dioxygenase-like protein 1(IDO2) belongs to the indoleamine 2,3-dioxygenase family. IDO2 can be detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. It also expressed at low level in testis and thyroid but not expressed in the majority of human tumor samples. IDO2 catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. It involved in immune regulation. IDO1 and IDO2 are 2 distinct enzymes which catalyze the same reaction. IDO2 affinity for tryptophan is much lower than that of IDO1. 50 % of Caucasians harbor polymorphisms which abolish IDO2 enzymatic activity. IDO2 is expressed in human tumors in an inactive form: tryptophan degradation is entirely provided by IDO1 in these cells. IDO2 may play a role as a negative regulator of IDO1 by competing for heme-binding with IDO1. Low efficiency IDO2 enzymes have been conserved throughout vertebrate evolution, whereas higher efficiency IDO1 enzymes are dispensable in many lower vertebrate lineages. IDO1 may have arisen by gene duplication of a more ancient proto-IDO gene before the divergence of marsupial and eutherian (placental) mammals.

注意事项

本司产品仅用于科研，不用于临床诊断和治疗

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