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| 产品名称 |
Recombinant Human CD58 (C-Fc) |
| 英文名称 |
CD58/LFA-3/Lymphocyte Function-associated Antigen 3 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Lymphocyte Function-associated Antigen 3 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
AAH05930 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
48.6 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Lymphocyte Function-Associated Antigen 3; Surface Glycoprotein LFA-3; CD58; LFA3；Ag3; CD58 antigen |
| 背景介绍 |
| Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
