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| 产品名称 |
Recombinant SARS-CoV-2 Guanine-N7_meth (N-6His) |
| 英文名称 |
Guanine-N7_meth/Guanine-N7_methyltransferase/NSP14 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
Please contact with the lab for this information |
| 蛋白构建 |
Recombinant 2019-nCoV Guanine-N7 methyltransferase is produced by our E.coli expression system and the target gene encoding Ala1-Gln527 is expressed with a 6His tag at the N-terminus. |
| Accession |
YP_009725309.1 |
| 表达宿主 |
E.coli |
| 种属 |
SARS-CoV-2 |
| 预测分子量 |
62.9 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, 2mM DTT, 20% Glycerol, 0.1% TritonX-100, pH 6.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| SARS-CoV 2 nsp14; SARS-CoV 2 ExoN; Guanine-N7 methyltransferase |
| 背景介绍 |
| The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3 to 5 direction and a N7-guanine methyltransferase activity. It may be involved in the proof-reading ability during the viral RNA replication and transcription. GTP, dGTP as well as cap analogs GpppG, GpppA and m7GpppG could be methylated by nsp14. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
