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| 产品名称 |
Recombinant Human IL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer Protein (C-Fc) |
| 英文名称 |
IL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant HumanIL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer is produced by our Mammalian expression system and the target gene encoding Met1-Ser212&Leu23-Asn254&Met1-Asp239 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
P14784&P01589&P31785 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
51.4&75.7 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, pH7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| IL-2 R beta & IL-2 R alpha & IL-2 R gamma |
| 背景介绍 |
| Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 consists of at least three distinct subunits, the alpha chain (IL-2Rα), the beta chain (IL-2Rβ), and the gamma chain (IL-2Rγ). Interleukin-2 (lL-2), one of the first lymphokines to be identified, plays a central role in the clonal expansion of activated T lymphocytes (T cells) by interacting with its specific cell surface receptor(IL-2 receptor). Antigen-specific, clonal proliferation of T cells is initiated via a process of signal transduction, wherein the specific interaction of the antigen/MHC molecule and T cell antigen receptor complex (TCR) triggers the expression of IL-2 and its homologous receptor (IL-2R). |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
