图文详情
18-Deoxyherboxidiene (RQN-18690A) is a potent inhibitor of angiogenesis. 18-Deoxyherboxidiene selectively acts on SF3b, a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. 18-Deoxyherboxidiene is a potent inhibitor of angiogenesis. Deoxyherboxidiene inhibits migration and tube formation in human umbilical vein endothelial cells (HUVEC) without significant cytotoxicity. 18-Deoxyherboxidiene has potential for cancer research.