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BuChE-IN-7 is a selective inhibitor targeting human butyrylcholinesterase (hBuChE) and equine butyrylcholinesterase (eqBuChE), demonstrating IC50 values of 40 nM and 80 nM, respectively. Demonstrating the ability to penetrate the blood-brain barrier, BuChE-IN-7 enhances cognitive functions and specifically augments situational and phobic memory, exhibiting a preference for novelty.