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PTP1B-IN-20 is a selective PTP1B (protein tyrosine phosphatase 1B) inhibitor, exhibiting an IC50 of 1.05 μM, and demonstrates selectivity over TCPTP (T-cell protein tyrosine phosphatase), which has an IC50 of 78.0 μM. This compound targets a crucial enzyme for the inhibition of type 2 diabetes, distinguishing itself by its preferential action on PTP1B over the closely related TCPTP.