图文详情
DXR inhibitor 11a, with an IC50 value of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum's growth in isolated human erythrocytes, with an IC50 of 0.37 µM.