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PF-07328948 is a branched chain ketone dehydrogenase kinase (BDK) inhibitor with oral biological activity. PF-07328948 can degrade branched chain ketone dehydrogenase (BCKDH) enzyme complex, thereby enhancing the catabolism of branched chain amino acids (BCAAs), and has potential inhibitory effects on heart failure, which can be used in heart failure related research.