图文详情
Tubulin inhibitor 26 (compound 3c) is an indazole derivative which is a potent tubulin inhibitor with noteworthy low nanomolar potency against HepG2, HCT116, SW620, HT29 and A549 cancer cell lines. Tubulin inhibitor 26 inhibits tumor cell in G2/M phase as well as induces cell apoptosis. Tubulin inhibitor 26 suppresses the growth of tumor in vivo without affecting the mice body weight [1].