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S-Methylglutathione (S-Methyl glutathione) is an S-substituted glutathione, an inhibitor of the 1-chloro-2,4-dinitrobenzene coupling catalyzed by transferase A and an XOCl scavenger.S-Methylglutathione inhibits glyoxalase 1 (glyoxalase 1), which induces the development of the glyoxalase 1 enzyme. S-Methylglutathione inhibits glyoxalase 1 (glyoxalase 1) and induces the formation of hydroid tentacle balls.