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Mouse monoclonal antibody to AKT

产品名：AKT antibody

货号：orb1474228

产品中文名：AKT antibody 抗体

产品详情链接：https://www.biorbyt.com/akt-antibody-orb1474228.html

Immunogen: Purified recombinant human AKT1 protein fragments expressed in E.coli.AKT1 interacts (via the C-terminus) with CCDC88A (via its C-terminus). Interacts with GRB10; the interaction leads to GRB10 phosphorylation thus promoting YWHAE-binding By similarity. Interacts with AGAP2 (isoform 2/PIKE-A); the interaction occurs in the presence of guanine nucleotides. Interacts with AKTIP. Interacts (via PH domain) with MTCP1, TCL1A AND TCL1B. Interacts with CDKN1B; the interaction phosphorylates CDKN1B promoting 14-3-3 binding and cell-cycle progression. Interacts with MAP3K5 and TRAF6. Interacts with BAD, PPP2R5B, STK3 and STK4. Interacts (via PH domain) with SIRT1. Interacts with SRPK2 in a phosphorylation-dependent manner. Interacts with RAF1. Interacts with TRIM13; the interaction ubiquitinates AKT1 leading to its proteasomal degradation. Interacts with TNK2 and CLK2. Interacts (via the C-terminus) with THEM4 (via its C-terminus). Interacts with and phosphorylated by PDPK1.AKT2 interacts (via PH domain) with MTCP1, TCL1A AND TCL1B. Interacts with CLK2, PBH2 and TRAF6. AKT3 interacts (via PH domain) with TCL1A; this enhances AKT3 phosphorylation and activation. Interacts with TRAF6.

Tested Applications: IP, WB

Application Dilutions: WB (1/500 - 1/1000), IP (1/10 - 1/50)

Reacts With: Human, Mouse, Rat

Conjugation: Unconjugated

Host: Mouse

Clonality: Monoclonal

Form/Appearance: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.

Preservative: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.

Source: Mouse

Storage Instructions: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Alternative Names: AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta; AKT3; PKBG; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2

Entrez: 29414, 208, 23797, 11652, 24185, 11651, 25233, 207, 10000

UniProt ID: Q9Y243, P47196, P31750, Q60823, P47197, Q9WUA6, Q63484, P31751, P31749

Target: AKT1; AKT2; AKT3

Note: For research use only.



英国biorbyt（www.biorbyt.com），成立于2011年，总部位于世界科技中心之一的英国剑桥郡，专注于生命科学和生物技术领域，系英国高品质生命科学试剂供应商。产品涉及各种科研领域，被许多知名杂志引用，并收到客户的良好反馈。