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Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity

产品名：Human TNFSF13B protein

货号：orb705331

产品详情链接：https://www.biorbyt.com/human-tnfsf13b-protein-orb705331.html

Alternative Names: B lymphocyte stimulator (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1)

Application Notes: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Purity: Greater than 93% as determined by SDS-PAGE.

Biological Origin: Homo sapiens (Human)

Protein Sequence: AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL

Molecular Weight: 46.6 kDa

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized TNFSF13B at 10 μg/ml can bind human BCMA, the EC50 of human TNFSF13B protein is 221.3-298.6 ng/ml. Human SIRPA protein His/Myc tag captured on COOH chip can bind Human CD47 protein Fc tag with an affinity constant of 19.1 nM as detected by LSPR Assay. Measured by its binding ability in a functional ELISA. Immobilized TNFSF13B at 2 μg/ml can bind TNFRSF13C, the EC50 is 9.943-15.72 ng/ml.

Expression Region: 134-285aa

Endotoxins: Less than 1.0 EU/ug as determined by LAL method.

Tag: N-terminal hFc-tagged

Preservative: Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4

Source: Mammalian cell

Form/Appearance: Lyophilized powder

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Uniprot ID: Q9Y275

Note: For research use only.






英国biorbyt（www.biorbyt.com），成立于2011年，总部位于世界科技中心之一的英国剑桥郡，专注于生命科学和生物技术领域，系英国高品质生命科学试剂供应商。产品涉及各种科研领域，被许多知名杂志引用，并收到客户的良好反馈。