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产品描述
CUSABIO's Human SARS-CoV-2 nucleoprotein (N) IgG Antibody ELISA Kit allows for in vitro qualitative detection of the IgG antibody-specific for SARS-CoV-2 N protein in human serum and plasma. This research-use only kit can be applied in the studies associated with COVID-19, infectious and severe pneumonia caused by SARS-CoV-2. It has been validated with high sensitivity, high specificity, and high precision.
Nucleoprotein is the most abundant protein in SARS-CoV-2. It packs the positive-sense single-stranded viral RNA into a helical ribonucleocapsid (RNP), forming the viral nucleocapsid (N). The N protein plays an important role in improving the efficiency of virus transcription and assembly. It is also involved in viral pathogenesis. N protein possessing an immunogenic effect makes it trigger an immune response, which leads to the production of IgM/G against SARA-CoV-2 N protein. SARS-CoV-2 N IgG antibodies appear in the serum after 2-3 weeks after the onset of the symptoms, peaks within the third week, and gradually declines to a lower level. IgG-specific for SARS-CoV-2 N protein rapidly increases to a higher level after a secondary infection and retains in the body for several months even years.
别名
N; Nucleoprotein; N; Nucleocapsid protein; NC; Protein N缩写
SARS-CoV-2 N Ab (IgG)Uniprot No
P0DTC9反应时间
1-5h样本体积
50-100ul检测波长
450 nm研究领域
Infectious Diseases测定原理
qualitative精密度
| Intra-assay Precision (Precision within an assay): CV%<15% | ||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||
| Inter-assay Precision (Precision between assays): CV%<15% | ||
| Three samples of known concentration were tested in twenty assays to assess. | ||
标准曲线
| Test parameter | specification | test result |
| Positive control | ≥0.6 | 0.867 |
| Negative control | ≤0.25 | 0.184 |
| Positive rate | 20，Positive | 100% |
| Negative rate | 20，Negative | 100% |
货期
3-5 working days
