产品描述

The human S100A12 ELISA Kit quantitates human S100A12 levels in serum and plasma. S100A12, also called calgranulin C, is a calcium-binding protein highly expressed in neutrophils and lowly expressed in lymphocytes and monocytes. It is secreted and upregulated during acute and chronic infection. Upon release, S100A12 functions as a proinflammatory alarmin. Elevated plasma levels of S100A12 are a new biomarker for many inflammatory diseases due to their significantly increased expression at inflamed sites. Additionally, S100A12 has been detected in many types of cancer such as oropharyngeal squamous cell carcinoma (OPSCC) and colorectal cancer, and is associated with proliferation, invasion, and migration of tumor cells. S100A12 expression is related to pathological features, including the tumor grade and stage as well as lymph node metastasis status.

This kit employs the sandwich-ELISA mechanism in conjugation with S100A12 antibody-S100A12 antigen-specific binding as well as HRP-TMB chromogenic reaction to measure the concentration of S100A12 in the samples. The kit is characterized by high sensitivity, strong specificity, good linearity, high recovery, and a precision of less than 10%.

别名

CAAF1 ELISA Kit; CAGC ELISA Kit; Calcitermin ELISA Kit; Calcium-binding protein in amniotic fluid 1 ELISA Kit; Calgranulin C ELISA Kit; Calgranulin-C ELISA Kit; Calgranulin-related protein ELISA Kit; CGRP ELISA Kit; EN RAGE ELISA Kit; EN-RAGE ELISA Kit; ENRAGE ELISA Kit; Extracellular newly identified RAGE-binding protein ELISA Kit; migration inhibitory factor-related protein 6 ELISA Kit; MRP6 ELISA Kit; Neutrophil S100 protein ELISA Kit; p6 ELISA Kit; Protein S100 A12 ELISA Kit; S100 calcium binding protein A12 ELISA Kit; S100 calcium-binding protein A12 (calgranulin C) ELISA Kit; S100 calcium-binding protein A12 ELISA Kit; S100A12 ELISA Kit; S10AC_HUMAN ELISA Kit

缩写

S100A12

Uniprot No

P80511

灵敏度

0.039ng/ml.

反应时间

1-5h

样本体积

50-100ul

检测波长

450 nm

研究领域

Signal Transduction

测定原理

quantitative

货期

3-5 working days