产品描述
TIMP1 (Tissue inhibitor of metalloproteinase 1) 是一种抑制金属蛋白酶的蛋白质,对细胞外基质的代谢和细胞的增殖、分化、凋亡等生物学过程具有重要作用。TIMP1的表达水平受到多种细胞因子的调节,并且参与多种生理和病理过程,如肿瘤发生和转移、心血管疾病、关节炎等。在正常情况下,TIMP1与基质金属蛋白酶 (MMPs) 形成1:1的复合物,维持基质的稳态,而在一些疾病中,TIMP1的表达水平异常升高,抑制了MMPs的活性,导致基质的过度积累。
华美生物所提供的Mouse tissue inhibitors of metalloproteinase 1,TIMP-1 ELISA Kit属于ELISA检测试剂盒,采用双抗夹心法定量检测鼠血清、血浆、细胞培养上清样本中的TIMP1,其灵敏度为0.110 ng/mL,检测范围为0.156 ng/mL-10 ng/mL。
别名
Timp1 ELISA Kit; Timp ELISA Kit; Timp-1 ELISA Kit; Metalloproteinase inhibitor 1 ELISA Kit; Collagenase inhibitor 16C8 fibroblast ELISA Kit; Erythroid-potentiating activity ELISA Kit; EPA ELISA Kit; TPA-S1 ELISA Kit; TPA-induced protein ELISA Kit; Tissue inhibitor of metalloproteinases 1 ELISA Kit; TIMP-1 ELISA Kit
缩写
TIMP1
Uniprot No
P12032
灵敏度
0.110 ng/mL
反应时间
1-5h
样本体积
50-100ul
检测波长
450 nm
研究领域
Cardiovascular
测定原理
quantitative
精密度
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays):CV%<10%
Three samples of known concentration were tested in twenty assays to assess.

线性度
To assess the linearity of the assay, samples were spiked with high concentrations of mouse TIMP-1in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

标准曲线
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.


货期
3-5 working days