产品描述

The human IL-5 ELISA kit is suitable for the quantitative determination of human IL-5 in different sample types, including serum, plasma, and tissue homogenates. This assay employs the bi-antibody sandwich technique and enzyme-substrate chromogenic reaction to quantify antigen levels in the sample. The amount of synthesized colored products is positively related to the analyte of interest in the sample.

IL-5 is a homodimeric cytokine responsible for the maturation of eosinophils in the bone marrow and their release into the blood. In humans, IL-5 functions exclusively on eosinophils and basophils and induces their maturation, growth, activation, and survival. In allergies, IL-5 does not take part in IgE synthesis rather than acting on mast cells to promote histamine release. IL-5 increases the expression of IL-2 receptors on B-cells and promotes B-cell proliferation and differentiation. IL-5 is associated with the pathogenesis of atopic diseases.

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