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收藏This human IL-24 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of human IL-24 in multiple samples, including serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the IL-24 levels in the sample and is measured at 450 nm through a microplate reader.
IL-24 is expressed primarily in T cells and macrophages. Different concentrations of IL-24 may present completely contrary bioactivity. A low concentration of IL-24 promotes inflammatory cytokine expression, resulting in the proinflammatory response. However, high levels of IL-24 strongly induce apoptosis of cancer cells. IL-24 is a potential anti-tumor agent and affects a broad array of cancers, which selectively inhibits tumor cell growth, invasion, metastasis, and angiogenesis, induces cancer-selective apoptosis, and stimulates an anti-cancer immune response, sensitizes cancer call to therapies.