产品描述

CUSABIO's human FOLR1 ELISA kit is an in vitro enzyme-linked immunosorbent assay for quantitatively measuring human FOLR1 in serum, plasma, or tissue homogenates. This assay uses the sandwich enzyme immunoassay technique in combination with the enzyme-substrate chromogenic reaction to quantify the analyte in the sample. The color develops positively to the amount of FOLR1 in samples. The color intensity is measured at 450 nm via a microplate reader.

FOLR1 is a glycosylphosphatidylinositol-linked protein that mediates cellular responses to folate, including cell division, proliferation, and tissue growth. FOLR1 binds folic acid and its reduced derivatives and is the transporter for 5-methyltetrahydrofolate into cells. It is involved in DNA replication and damage repair. FOLR1 is overexpressed in various epithelial malignancies including ovarian, breast, renal, and lung cancers. The overexpression of FOLR1 is often related to increased cancer progression and poor patient prognosis.

别名

adult ELISA Kit; Adult folate binding protein ELISA Kit; Adult folate-binding protein ELISA Kit; FBP ELISA Kit; Folate Binding Protein ELISA Kit; Folate Receptor 1 Adult ELISA Kit; Folate receptor 1 ELISA Kit; Folate Receptor 1 Precursor ELISA Kit; Folate receptor adult ELISA Kit; Folate receptor alpha ELISA Kit; Folate receptor ELISA Kit; FOLR ELISA Kit; FOLR1 ELISA Kit; FOLR1_HUMAN ELISA Kit; FR alpha ELISA Kit; FR-alpha ELISA Kit; FRalpha ELISA Kit; KB cells FBP ELISA Kit; MOV18 ELISA Kit; Ovarian cancer associated antigen ELISA Kit; Ovarian tumor associated antigen ELISA Kit; Ovarian tumor associated antigen MOv18 ELISA Kit; Ovarian tumor-associated antigen MOv18 ELISA Kit

缩写

FOLR1

Uniprot No

P15328

灵敏度

0.09 ng/ml

反应时间

1-5h

样本体积

50-100ul

检测波长

450 nm

研究领域

Tags & Cell Markers

测定原理

quantitative

精密度

 

线性度

To assess the linearity of the assay, samples were spiked with high concentrations of human FOLR1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
		Sample		Serum(n=4)
1:1		Average %		92
		Range %		85-97
1:2		Average %		95
		Range %		88-99
1:4		Average %		91
		Range %		86-95
1:8		Average %		94
		Range %		87-98

回收率

 

标准曲线

 

货期

3-5 working days