产品描述

This human GCP-2 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of human GCP-2 in serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the GCP-2 levels in the sample and is measured at 450 nm through a microplate reader.

GCP-2, also known as CXCL6, is a neutrophil-recruiting ELR+ chemokine that signals through the receptors CXCR1 and CXCR2 that are expressed on neutrophils. CXCL6-CXCR1/2 signaling mediates multiple biological processes such as inflammation, immunoreaction, cell growth, and metastasis in humans. It also promotes human hepatocyte proliferation through the CXCR1-NF-κB pathway and suppresses collagen I secretion by hepatic stellate cells. CXCL6 is involved in cancer angiogenesis, metastasis, and immune response. CXCL6 promotes the growth and metastasis of various cancers, including non-small cell lung cancer and osteosarcoma (OS).

别名

C X C motif chemokine 6 ELISA Kit; Chemokine (C X C motif) ligand 6 ELISA Kit; Chemokine alpha 3 ELISA Kit; CKA 3 ELISA Kit; CKA-3 ELISA Kit; CKA3 ELISA Kit; CXCL 6 ELISA Kit; CXCL6 ELISA Kit; CXCL6_HUMAN ELISA Kit; GCP 2 ELISA Kit; GCP-2 ELISA Kit; Granulocyte chemotactic protein 2 ELISA Kit; N-processed variant 3 ELISA Kit; SCYB6 ELISA Kit; Small inducible cytokine B6 ELISA Kit; Small inducible cytokine subfamily B (Cys X Cys) member 6 ELISA Kit; Small inducible cytokine subfamily B (Cys X Cys) member b ELISA Kit; Small-inducible cytokine B6 ELISA Kit

缩写

CXCL6

Uniprot No

P80162

灵敏度

19.5 pg/mL

反应时间

1-5h

样本体积

50-100ul

检测波长

450 nm

研究领域

Immunology

测定原理

quantitative

货期

3-5 working days