产品描述

The product CSB-EL008626HU is a sandwich ELISA kit developed to measure levels of human FGF20 in multiple samples, including serum, plasma, cell lysates, or tissue homogenates. The enzyme-substrate chromogenic reaction is also used to amplify the signal and quantify the levels of the analyte through the intensity of the colored product. The color intensity positively correlates with the amount of FGF20 bound in the initial step.

FGF20-FGFR1 signaling is essential for cochlear hair cell (HC) and supporting cell (SC) differentiation. FGF20 is expressed in hair placodes and is induced by and functions downstream from epithelial ectodysplasin (Eda)/Edar and Wnt/β-Catenin signaling to initiate the formation of the underlying dermal condensation. It controls the formation of primary and secondary dermal condensations in developing hair follicles and subsequent formation of guard, awl, and Duchene's hairs.

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